EVIDENCE-BACKED

Jellyfish Jolt

An emerging collagen source from the sea.

Skin & Beauty

MitoLifeCell
Jellyfish Jolt

$35.00

Your discount applies with code HOLISTICLOVE.

When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.

What it is

Collagen sourced from wild-caught jellyfish, a newer entry in the collagen world. Jellyfish are unusually collagen-rich, and the extract is used much like other collagen sources -- as a supply of the amino-acid building blocks for joint and skin tissue.

Why the evidence supports it

Honesty sets the tier here: jellyfish collagen is an emerging ingredient with a thinner, mostly pre-clinical research base -- early lab work shows its collagen interacts with immune cells, but human trials lag well behind marine or bovine collagen. What it shares with any collagen source is the mechanism: supplying the raw amino acids the cell's Build function uses for skin and connective tissue. So expectations stay realistic -- a novel collagen option for people who rotate their sources, with the evidence still early.

What it supports

  • Supports joints and connective tissue
  • Supports skin as part of a balanced routine
  • Provides an emerging marine collagen source
  • A novel option for people who rotate their collagen sources

Which function it supports

CellBuild
healthy inflammation response

Ties to the cell's Build function -- collagen supplies raw material for skin and connective tissue. Framed as an emerging ingredient, not a proven outcome.

Learn the why behind this pillar

How it relates to your cells and mind

Every product here ties back to a specific job your body does. This one touches the functions below -- follow either link to see the mechanism in full, then dig into the studies.

What it is made of -- and the mechanisms behind it

Each ingredient acts on several of the body's functions. Taken together, this product touches these cell and mind functions -- follow any to see the mechanism in full.

The ingredients

Mechanisms drawn from our ingredient knowledge base (1 profiled ingredients). Structure and function only -- not a treatment claim.

What’s actually in it

Label revision label image on the product page, read 2026-09-12

Transcribed from the manufacturer’s official Product Information Page, exactly as printed.

Supplement Facts panel for Jellyfish Jolt (Wild-Caught)
Amount per 1 capsuleAmount% DV
kollaJelledible jellyfish collagen (Stomolophus meleagris and Rhizostoma pulmo)1 g
Servings per container:
30
Other ingredients:
Vegetarian capsule (hypromellose and water), bamboo extract.
Allergens:
Derived from jellyfish -- relevant to shellfish/marine sensitivities

Source: official Product Information Page . Amounts are the manufacturer’s, not ours. Structure and function only -- nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease.

The science on the ingredients

These studies are research on the ingredients and mechanisms in this product, not on the finished product itself, and they are shown for education. For this ingredient most of the published work is laboratory or animal research rather than human trials, so read it as biology worth knowing rather than proof of an effect in people. Nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease. Talk to your own provider about what is right for you.

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  • Identification of Novel Anti-Inflammatory Peptides from Jellyfish <i>Nemopilema nomurai</i> Enzymatic Hydrolysate: An Integrated In Silico Analysis and Cellular EvaluationEmerging2026

    Three peptides from Nemopilema nomurai hydrolysate docked to the TLR4/MD-2 complex at -8.4 to -8.3 kcal per mole and inhibited LPS-induced nitric oxide, TNF-alpha and IL-1beta in RAW264.7 macrophages.

    Wen Shen; Xueqin Wang; Rongfeng Li; Song Liu; Ronge Xing; Pengcheng Li; Huahua Yu

  • The wound healing potential of collagen peptides derived from the jellyfish Rhopilema esculentumLineage2019

    Jellyfish-derived collagen peptides enhanced migration of human umbilical vein endothelial cells in a lab wound-scratch assay, and oral peptides improved wound healing signs, including re-epithelialization and collagen deposition, in mice.

    Felician FF, Yu RH, Li MZ, Li CJ, Chen HQ, Jiang Y, Tang T, Qi WY, Xu HM -- Chinese Journal of Traumatology

  • Methacrylated chitosan/jellyfish collagen membranes as cell instructive platforms for liver tissue engineering.2024

    In vitro, blending methacrylated chitosan with jellyfish collagen created a membrane platform that supported hepatocyte growth and differentiation for potential use in liver tissue engineering.

    Morelli S; D'Amora U; Piscioneri A; Oliviero M; Scialla S; Coppola A; De Pascale D; Crocetta F; De Santo MP; Davoli M; Coppola D; De Bartolo L -- International journal of biological macromolecules

  • Black Sea-Derived Biomaterials for Wound-Healing ApplicationsEmerging2026

    A biocomposite of jellyfish collagen, crab chitosan and green algal polysaccharides from the Black Sea showed antioxidant and antimicrobial activity and supported fibroblast and keratinocyte viability and scratch closure at lower concentrations.

    Cadar E; Roncea FN; Roșca AC; Peșterău AM; Albu CC; Bubulac L; Drăgan LA; Jurja S; Bogdan-Andreescu CF; Stoicescu I; Sirbu R -- International journal of molecular sciences

  • Isolation, Characterization and Evaluation of Collagen from Jellyfish Rhopilema esculentum Kishinouye for Use in Hemostatic ApplicationsLineage2017

    Collagen isolated from jellyfish mesoglea was structurally type I collagen and improved clotting/hemostatic performance in a rat tail-amputation model.

    Cheng X, Shao Z, Li C, Yu L, Raja MA, Liu C -- PLOS ONE

  • Jellyfish Rhizostoma pulmo collected off Goa Coast (India) as a rich source of tryptophan containing collagen and its enhanced antioxidant potential.2023

    Extraction from discarded Rhizostoma pulmo jellyfish yielded a high 47% recovery of type I collagen containing tryptophan, an essential amino acid the researchers link to potential benefits for neurotransmission and cognitive function.

    James S; Tilvi S; Khandeparker R; Sreepada RA; Thakur N; Gauthankar M -- Journal of food science and technology

  • Isolation, Characterization and Biological Evaluation of Collagen from Rhizostoma pulmo Jellyfish from the Sea of Azov for Biomedical ApplicationsEmerging2026

    Acid-soluble collagen extracted from Azov Sea Rhizostoma pulmo jellyfish gave a 26.2% yield with type I profile, low endotoxin at 0.461 endotoxin units per microlitre, no cytotoxicity to fibroblasts, and 80-micrometre porous scaffolds.

    Kit O; Golovin S; Kirichenko E; Sereda A; Gordeeva Y; Sadyrin E; Nikolaev A; Antipov P; Logvinov A; Kaplya M; Abdulkadyrov M; Rodkin S -- Marine drugs

  • Advanced Polymeric Membranes as Biomaterials Based on Marine Sources Envisaging the Regeneration of Human Tissues.2023

    Chemical-free cross-linked polymeric membranes made from marine-origin biopolymers formed stable polyelectrolyte complexes, proposed as biomaterial scaffolds to support regeneration of damaged tissues like articular cartilage.

    Carvalho DN; Lobo FCM; Rodrigues LC; Fernandes EM; Williams DS; Mearns-Spragg A; Sotelo CG; Perez-Martín RI; Reis RL; Gelinsky M; Silva TH -- Gels (Basel, Switzerland)

  • High vulnerability of jellyfish ephyras (Aurelia aurita) and copepods (Calanoids) to understudied organic UV filters: A multi-trophic ecotoxicological assessmentEmerging2026

    Across five marine species, the sunscreen chemical octisalate proved highly toxic to jellyfish larvae and copepods at low milligram-per-liter doses, jellyfish were the most sensitive organisms tested, and commercial sunscreen blends were generally less toxic than the pure chemicals alone.

    Borja Mercado-Casares; Irene Diago-Sánchez; Isabel Piera-Martínez; Miguel Candelas; Oscar Andreu-Sánchez

  • Extracellular matrix type 0: From ancient collagen lineage to a versatile product pipeline - JellaGel™.2023

    A jellyfish-derived extracellular matrix biomaterial (JellaGel) supported neuron-astrocyte co-culture, spheroid formation, and 3D stem cell culture with more homogeneous structural properties than existing mammalian-derived matrices.

    Faruqui N; Williams DS; Briones A; Kepiro IE; Ravi J; Kwan TOC; Mearns-Spragg A; Ryadnov MG -- Materials today. Bio

  • Collagen from Salted Jellyfish (Rhopilema esculentum): Structural Characterization, Emulsifying Properties and Wound Healing PotentialEmerging2026

    Pepsin-soluble collagen from salted jellyfish retained an intact triple-helix structure with a denaturation temperature near 36 degrees C and formed stable gels, characterizing structural and wound-healing-relevant properties of this collagen source.

    Hu B; Zong Z; Han L; Yao Z; Yang J; Liu R; Cao J; Al-Assaf S -- Gels

  • Anti-obesity effect of collagen peptides obtained from Diplulmaris antarctica, a jellyfish of the Antarctic region.2023

    In rats fed a high-calorie diet, hydrolyzed collagen peptides from the Antarctic jellyfish Diplulmaris antarctica reduced body weight gain, fasting glucose, glycated hemoglobin, and insulin levels while restoring superoxide dismutase activity and reducing oxidatively modified proteins.

    Raksha N; Halenova T; Vovk T; Kostyuk O; Synelnyk T; Andriichuk T; Maievska T; Savchuk O; Ostapchenko L -- Croatian medical journal

  • Characterization of a New Biocomposite Based on Bioactive Compounds from Ganoderma lucidum and Jellyfish Collagen Destined for In Vitro Evaluation of Antitumor Effects in the Oral CavityEmerging2026

    A biocomposite of Ganoderma lucidum extract in Rhizostoma pulmo collagen preserved type I collagen structure, showed stronger antioxidant and antimicrobial activity than collagen alone, and dose-dependently reduced viability and migration of two oral carcinoma cell lines.

    Pascale C; Burcea A; Bogdan-Andreescu CF; Cadar E; Popescu A; Negreanu-Pirjol T; Busuricu F; Pesterau AM; Rosca AC; Sirbu R -- Pharmaceuticals (Basel, Switzerland)

  • Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging tissue engineering.2020

    Jellyfish collagen combined with chitosan and fucoidan formed chemical-free crosslinked cryogels that preserved collagen's triple-helix structure, showing potential as a biomaterial scaffold for tissue engineering.

    Carvalho DN; López-Cebral R; Sousa RO; Alves AL; Reys LL; Silva SS; Oliveira JM; Reis RL; Silva TH -- Biomedical materials (Bristol, England)

  • A Review of the Chemical Properties, Mechanisms of Action, and Structure-Activity Relationships of Jellyfish ToxinsEmerging2026

    A review of jellyfish toxins summarises their physicochemical properties, molecular mechanisms of action, transformation in organisms and structure-activity relationships, supporting antivenom development and marine drug design.

    Peng Wang; Long Li; Cong Kong; Zhiyu Fu; Yunfeng Li; Hai Chi

  • Guided Bone Regeneration Using Collagen Scaffolds, Growth Factors, and Periodontal Ligament Stem Cells for Treatment of Peri-Implant Bone Defects In Vivo.2017

    In minipigs with peri-implant bone defects, plain collagen powder produced better new bone formation than jellyfish collagen matrix or growth-factor-enhanced scaffolds, with no combination outperforming a blank control after 120 days of healing.

    Kämmerer PW; Scholz M; Baudisch M; Liese J; Wegner K; Frerich B; Lang H -- Stem cells international

  • Development of an H<sub>2</sub>S-Associated Matrix Based on <i>Rhizostoma pulmo</i> Jellyfish Collagen: A Pilot Evaluation of Neuroprotective Effects and Cx43/p53 Regulation in Penetrating Traumatic Brain InjuryEmerging2026

    In a mouse model of severe traumatic brain injury, a jellyfish collagen matrix modified with sodium thiosulfate filled the defect, reduced p53 accumulation and neuronal damage and prevented connexin 43 dysregulation.

    Stanislav Rodkin; Maria Kaplya; Sergey Golovin; Evgeniya Kirichenko; Chizaram Nwosu; Aleksandr Logvinov; Alina Sereda; Yulia Gordeeva; Aleksandr Romanov; Stanislav Bachurin

  • Jellyfish collagen matrices conserve the chondrogenic phenotype in two- and three-dimensional collagen matrices.2017

    In cell culture, jellyfish collagen matrices preserved the round chondrogenic phenotype of porcine chondrocytes in both two- and three-dimensional cultures, comparably to vertebrate type II collagen.

    Sewing J; Klinger M; Notbohm H -- Journal of tissue engineering and regenerative medicine

  • Jellyfish collagen ameliorates collagen-induced arthritis CIA in Sprague Dawley rats by modulating inflammatory mediators by inhibiting the NF κB and JAK STAT pathwaysEmerging2025

    In 28 male Sprague Dawley rats with collagen-induced arthritis, oral jellyfish collagen, best at 100 ug/kg, downregulated NF-kB, IL-1beta, TNF-alpha, COX-2, JAK1 and STAT3 while upregulating TGF-beta and IL-10.

    Mona Assas; Amal Shams; Abdallah S Salah; Mohamed M Zayed; Ayman Atiba; Doaa H Assar; Rasha A Al Wakeel; Alaa Elgaabari; Zizy I Elbialy

  • Modulation of chondrogenic differentiation of human mesenchymal stem cells in jellyfish collagen scaffolds by cell density and culture medium.2017

    Study found that cell density and culture medium composition influenced chondrogenic differentiation of human mesenchymal stem cells grown on jellyfish collagen scaffolds, informing development of combined osteochondral tissue regeneration media.

    Pustlauk W; Paul B; Brueggemeier S; Gelinsky M; Bernhardt A -- Journal of tissue engineering and regenerative medicine

  • Aurelia aurita jellyfish collagen: Recovery propertiesEmerging2025

    Acetic acid extraction of Aurelia aurita jellyfish gave a very low collagen yield of 0.0185% or less; the type I collagen was not cytotoxic to keratinocytes and increased wound healing rate by 24.5% in a model.

    Noora Barzkar; Stanislav Sukhikh; Anastasiia Zhikhreva; Elizaveta Cheliubeeva; Anastasia Kapitunova; Danil Malkov; Olga Babich; Yuliya Kulikova -- Foods and Raw Materials

  • Isolation, characterization and biological evaluation of jellyfish collagen for use in biomedical applications.2011

    In lab cell tests, collagen extracted from Rhizostoma pulmo jellyfish showed similarly low toxicity to mammalian type I collagen, though heparin blocked cell attachment to jellyfish collagen by 55 percent, more than seen with mammalian collagen.

    Addad S; Exposito JY; Faye C; Ricard-Blum S; Lethias C -- Marine drugs

  • Marine Jellyfish Collagen and Other Bioactive Natural Compounds from the Sea, with Significant Potential for Wound Healing and Repair MaterialsEmerging2025

    A composite hydrogel of Rhizostoma pulmo jellyfish collagen peptides and Cystoseira barbata alga extract showed synergistic effects, enhancing fibroblast and keratinocyte migration and proliferation in vitro wound-healing assays.

    Ana-Maria Pesterau; Antoanela Popescu; Rodica Sirbu; Emin Cadar; Florica Busuricu; Ana-Maria Laura Dragan; Carolina Pascale; Ana-Maria Ionescu; Claudia Florina Bogdan-Andreescu; Marius-Daniel Radu; Cezar Laurentiu Tomescu

  • Characterization of heterotrimeric collagen molecules in a sea-pen (Cnidaria, Octocorallia).1992

    Study characterized the heterotrimeric collagen molecules of the sea-pen Veretillum, a primitive cnidarian, finding a distinct molecular chain structure that differs from previously described sea anemone and jellyfish collagen, informing understanding of collagen evolution.

    Tillet-Barret E; Franc JM; Franc S; Garrone R -- European journal of biochemistry

Balanced by design -- we show supporting and contradicting findings. Search all studies

No product works in isolation

Every cell function above -- Sense, Exchange, Transform, Build, Maintain, Adapt -- needs the same broad base of optimal micronutrient levels running underneath it, all the time. Jellyfish Jolt is not a stand-alone fix; it is one piece that plugs into that larger system. The foundation comes first, and this supports it.

Stacks well with

Pick your goal -- here is what Jellyfish Jolt pairs with for each. Nothing works in isolation; these share the same systems.

Foundational, or targeted?

Not everything in the shop is meant to be taken forever. Some products here are foundational -- a daily nutrient base built for long-term, ongoing use. Others are targeted -- shorter-term support for a specific season, not a lifelong habit. If you are not sure which one this is, that is a fair question to ask us before you buy.

Learn more, on your terms

Do not take our word for it -- go read. Each topic below opens a pre-loaded search so you can explore the nutrient, the mechanism, or the device for yourself.

Search the full studies library

How to use it

Take the daily serving with water. Collagen support generally rewards consistency over weeks. Follow the label.

Use code HOLISTICLOVE at checkout.

Where to get it

Ready when you are. This link takes you to the official, verified source for this product.

Get Jellyfish Jolt

Optimal nutrients are the definition of longevity

Long-term cell function depends on having what it needs, at the level it needs it, for as long as it needs it. That is the whole thesis behind everything we point you to here.

When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.

Jellyfish Jolt is collagen sourced from wild-caught jellyfish, a newer entry in the collagen world. People use it much like other collagen sources, for joint and skin support. It fits people who like to rotate their collagen sources and are curious about an emerging option.

FAQ

What does Jellyfish Jolt support?

It supports joints and connective tissue and supports skin as part of a balanced routine, provides an emerging marine collagen source, and is a novel option for people who rotate their collagen sources.

How do I take it?

Take the daily serving with water. Collagen support generally rewards consistency over weeks. Follow the label.

What makes it different?

Jellyfish collagen is an emerging ingredient with a thinner research base than marine or bovine collagen, so expectations are set honestly -- a novel source people try for joint and skin support.