When you buy through our links, we earn a small commission — and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
What it is
A once-daily hair, skin, and nail formula built around biotin (vitamin B7, 2,500 mcg) and a clinically studied grapefruit-and-rosemary polyphenol pairing, backed by antioxidant vitamins A (as beta-carotene), C, and E and a B-complex. Biotin is a cofactor the body uses to make keratin, while the grapefruit and rosemary extracts are studied for helping skin resist everyday environmental and light stress. It is aimed at the ordinary nutritional side of hair, skin, and nail health, not at treating hair loss or nail disease.
Why the evidence supports it
The two standout ingredients each have their own research: biotin is a genuine, if uncommon, factor in hair and nail changes and is studied for nail strength, and the grapefruit-plus-rosemary polyphenol combination has human and cell work on protecting skin proteins like collagen and elastin from oxidative and photo-stress. Vitamins C and E and beta-carotene add recognized antioxidant support, with vitamin C also a cofactor for the skin's own collagen synthesis. The honest note is that the biotin here sits far above the level the body can actually use, which is common in this category and no advantage. Taken for the long haul, it is an evidence-based way to support the cell's Build function — the cofactors and antioxidants the cells that build keratin and skin structure rely on — with hair and nail changes taking months to show.
What it supports
- Supports the everyday nutrient needs behind healthy hair growth
- Supports nail strength and structure
- Provides biotin (vitamin B7), a cofactor nutrient for keratin production
- Complements a protein- and mineral-sufficient diet
Which function it supports
Ties to the cell's Build function — biotin, antioxidant vitamins, and the grapefruit-and-rosemary polyphenols are the cofactors and protective compounds the cells that build hair, skin, and nail keratin rely on.
Learn the why behind this pillarHow it relates to your cells and mind
Every product here ties back to a specific job your body does. This one touches the functions below — follow either link to see the mechanism in full, then dig into the studies.
What it is made of — and the mechanisms behind it
Each ingredient acts on several of the body's functions. Taken together, this product touches these cell and mind functions — follow any to see the mechanism in full.
The ingredients
Mechanisms drawn from our ingredient knowledge base (3 profiled ingredients). Structure and function only — not a treatment claim.
The science on the ingredients
Exploring the Link Between Biotin Metabolism and Brucella Virulence: A Study on BioA.2026
Disrupting the biotin biosynthesis gene BioA in Brucella reduced its outer membrane integrity, cut intracellular macrophage survival by about 95%, and lowered bacterial virulence gene expression, suggesting BioA as an anti-brucellosis target.
Liu D; Quan H; Liu M; Xiao L; Jiao L; Gong X; Zeng Q; Chen Q — Pathogens (Basel, Switzerland)
Biological properties of vitamins of the B-complex, part 2 - vitamins B6 and B7 (biotin, vitamin H).2025
A review describes vitamins B6 and B7 (biotin) as essential water-soluble cofactors for numerous enzymatic reactions, noting biotin's additional role in gene expression regulation through protein biotinylation.
Dias P; Siatka T; Vopršalová M; Moravcová M; Pourová J; Přívratská N; Krčmová LK; Javorská L; Mladěnka P — Nutrition research reviews
Biotin Induces Inactive Chromosome X Reactivation and Corrects Physiopathological Alterations in Beta-Propeller-Protein-Associated Neurodegeneration.2025
In cellular models of beta-propeller-protein-associated neurodegeneration, biotin supplementation increased histone biotinylation to reactivate the normal WDR45 allele on the inactive X chromosome, correcting autophagy, iron metabolism, and bioenergetic defects.
Reche-López D; Romero-González A; Álvarez-Córdoba M; Suárez-Carrillo A; Cilleros-Holgado P; Piñero-Pérez R; Gómez-Fernández D; Romero-Domínguez JM; López-Cabrera A; González-Granero S; García-Verdugo JM; Sánchez-Alcázar JA — International journal of molecular sciences
Biotin: DNA to diet.2025
A review found that biotin serves as an essential cofactor in fatty acid synthesis, oxidation, amino acid metabolism, and gluconeogenesis, while its strong affinity for avidin also makes it useful as a biochemical diagnostic sensor.
Karalia S; Meena VK — The Journal of nutritional biochemistry
Immunoassay design and biotin interference.2022
A review found that biotin acts as a cofactor for carboxylase enzymes involved in gluconeogenesis and fatty acid synthesis, and that high-dose supplementation can interfere with clinical immunoassay results.
Dasgupta A — Advances in clinical chemistry
Pharmacological Effects of Biotin in Animals.2017
Review summarizes how biotin, beyond its role as a carboxylase coenzyme, has additional pharmacological actions in animals at higher doses, while noting that biotin's potential toxic effects at these pharmacological concentrations remain poorly studied.
Riveron-Negrete L; Fernandez-Mejia C — Mini reviews in medicinal chemistry
Mechanisms of biotin-regulated gene expression in microbes.2016
Review describes how bacteria regulate biotin-related genes through transcriptional repressors like BioR, showing this essential vitamin cofactor can itself control gene expression with potential synthetic biology applications.
Satiaputra J; Shearwin KE; Booker GW; Polyak SW — Synthetic and systems biotechnology
Dietary Lithium, Silicon, and Boron: An Updated Critical Review of Their Roles in Metabolic Regulation, Neurobiology, Bone Health, and the Gut MicrobiomeExpert review2026
This updated review covers the emerging evidence for lithium, silicon, and boron as trace dietary factors relevant to metabolism, bone, and brain health.
Study authors — Nutrients
Silicon: A neglected micronutrient essential for bone healthExpert review2021
This review summarizes decades of evidence linking dietary silicon intake to bone mineral density and to collagen-proteoglycan crosslinking in connective tissue.
Rondanelli M, Faliva MA, Peroni G, Gasparri C, Perna S, Riva A, Petrangolini G, Tartara A — Experimental Biology and Medicine
Oxidative Stress Biomarkers in Silicosis: A Systematic Review.2026
Systematic review found malondialdehyde levels were elevated and superoxide dismutase activity reduced in silicosis patients compared with unexposed controls, indicating amplified lipid peroxidation and impaired antioxidant defense.
Pau MC; Zinellu E; Piras B; Nardi A; Lacana MR; Scala C; Zinellu A; Mangoni AA; Carru C; Fois AG; Caramori G; Pirina P — Diseases (Basel, Switzerland)
The Combined Role of Silanols and Oxidative Stress in Determining Engineered Stone Dust Toxicity.2026
Engineered stone dust's surface silanol chemistry and oxidative reactivity, studied in simulated lung fluids, damaged model cell membranes, offering mechanistic insight into the occupational lung disease silicosis.
Pavan C; Fimiani M; Cananà S; Diana A; Marafante M; Bertinetti S; Escolano-Casado G; Mino L; Pisaniello D; Leinardi R; Tomatis M; Turci F — ACS organic & inorganic Au
Do Forms of Silicon Other than Orthosilicic Acid, Application Date and Dose Have a Beneficial Effect on Sugar Beet Yield?2026
In a three-year field trial, foliar calcium silicate and sodium metasilicate application increased sugar beet root yield and sugar content more than micronized silica, while product dose had essentially no significant effect on measured parameters.
Artyszak A; Gozdowski D; Litwińczuk-Bis M — Plants (Basel, Switzerland)
Mosla chinensis Maxim extracts exert anti-inflammatory, antioxidant, and antifibrotic effects in silicosis.2026
In mice, a plant extract reduced silica-induced lung fibrosis by restoring antioxidant enzymes, lowering inflammatory cytokines, and blocking TGF-beta/Smad-driven epithelial-to-mesenchymal transition in lung tissue.
Wu ST; Huang CW; Lee TH; Ku HC — Journal of ethnopharmacology
Enhancing food safety and security through silicon-based approaches in pre-harvest and post-harvest pest management.2025
Silicon accumulates in plant cell walls as amorphous silica, strengthening stress resistance and acting as a physical barrier against pests, a mechanism relevant to silicon's role in plant-based food security.
Kanakhara M; Panneerselvam A; Packirisamy P; Ezil Vendan S — Pest management science
Silicon-mediated modulation of maize growth, metabolic responses, and antioxidant mechanisms under saline conditions.2025
In maize under salt stress, exogenous silicon reduced sodium uptake and boosted protective secondary metabolites like anthocyanin, ascorbic acid, phenols, and flavonoids, mitigating salinity's damage to growth and antioxidant enzyme activity.
Ullah MS; Mahmood A; Alawadi HFN; Seleiman MF; Khan BA; Javaid MM; Wahid A; Abdullah F; Wasonga DO — BMC plant biology
Comparative study of silica and silica-decorated ZnO and ag nanocomposites for antimicrobial and photocatalytic applications.2025
Study found green-synthesized zinc oxide-silica and silver-silica nanocomposites achieved strong antimicrobial and photocatalytic pollutant degradation, with ZnO-silica reaching 75% degradation of a test pollutant, offering eco-friendly disinfection materials.
Ali A; Ali SR; Hussain R; Anjum R; Liu Q; Elshikh MS; Alkubaisi N; Iqbal R; Tabor S; Gancarz M — Scientific reports
Silica dust exposure and associated pulmonary dysfunction among mine workers.2025
In a study of 145 silica-exposed mine workers versus unexposed controls, exposure was linked to significantly reduced lung function, radiological lung damage, higher lipid peroxidation, lower antioxidant enzyme activity, and signs of systemic inflammation.
Batool AI; Shaheen R; Naveed NH; Tabassum T; Rehman MFU; Naz S; Habib SS; Mohany M — Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
Strict Verification of Multiple Indefinite Causal Orders on a Programmable Silicon-Photonic Quantum Chip2024
This paper reports experimental verification of multiple types of indefinite causal order using a programmable silicon-photonic quantum chip, contributing to theoretical resource frameworks for the phenomenon.
Yahohao Deng; Jianwei Wang — CLEO 2024
The glycyl-l-histidyl-l-lysine-Cu2+ tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6.2024
In a mouse model of silicosis, a copper-binding tripeptide called GHK-Cu reduced lung inflammation and fibrosis by binding the protein peroxiredoxin 6 in alveolar macrophages, a disease with no specific medication.
Bian Y; Deng M; Liu J; Li J; Zhang Q; Wang Z; Liao L; Miao J; Li R; Zhou X; Hou G — Redox biology
Cuprorivaite microspheres inhibit cuproptosis and oxidative stress in osteoarthritis via Wnt/β-catenin pathway.2024
In cell and mouse models of osteoarthritis, cuprorivaite microspheres containing silica reduced inflammatory, oxidative stress, and cuproptosis markers in chondrocytes while enhancing extracellular matrix components via the Wnt/beta-catenin pathway.
Li B; Jiang T; Wang J; Ge H; Zhang Y; Li T; Wang C; Wang W — Materials today. Bio
Role of metabolic reprogramming in pro-inflammatory cytokine secretion from LPS or silica-activated macrophages.2022
LPS-stimulated macrophages boost glycolysis and block succinate dehydrogenase to drive IL-1beta and TNF-alpha secretion, with glycolysis inhibition selectively blocking IL-1beta, while silica particles trigger distinct immunometabolic responses in macrophages.
Marrocco A; Ortiz LA — Frontiers in immunology
Extracellular signal-regulated kinase signaling pathway and silicosis.2021
Silicosis, a scarring lung disease from inhaling crystalline silica particles, involves activation of the extracellular signal-regulated kinase (ERK) pathway among other complex signaling mechanisms still being mapped.
Xie Y; Ma J; Yang M; Fan L; Chen W — Toxicology research
Pathophysiology of systemic sclerosis.2021
A review found that environmental exposures such as silica are considered contributing factors to systemic sclerosis, alongside genetic and epigenetic factors involved in immune activation and tissue fibrosis.
Thoreau B; Chaigne B; Renaud A; Mouthon L — Presse medicale (Paris, France : 1983)
Inhibitory effects of orthosilicic acid on osteoclastogenesis in RANKL-stimulated RAW264.7 cells.2021
In RANKL-stimulated cultured cells, orthosilicic acid directly inhibited osteoclast formation at a specific stage of development, adding to evidence that silicon supports bone metabolism partly through effects beyond osteoblast stimulation.
Magnusson C; Uribe P; Jugdaohsingh R; Powell JJ; Johansson A; Ransjö M — Journal of biomedical materials research. Part A
Balanced by design — we show supporting and contradicting findings. Search all studies
No product works in isolation
Every cell function above — Sense, Exchange, Transform, Build, Maintain, Adapt — needs the same broad base of optimal micronutrient levels running underneath it, all the time. Multi Beauty is not a stand-alone fix; it is one piece that plugs into that larger system. The foundation comes first, and this supports it.
Stacks well with
Pick your goal — here is what Multi Beauty pairs with for each. Nothing works in isolation; these share the same systems.
For Skin & Beauty
Foundational, or targeted?
Not everything in the shop is meant to be taken forever. Some products here are foundational — a daily nutrient base built for long-term, ongoing use. Others are targeted -- shorter-term support for a specific season, not a lifelong habit. If you are not sure which one this is, that is a fair question to ask us before you buy.
Learn more, on your terms
Do not take our word for it — go read. Each topic below opens a pre-loaded search so you can explore the nutrient, the mechanism, or the device for yourself.
Search the full studies libraryHow to use it
Take the labeled daily serving with a meal. Hair and nail changes take months to show, since both grow slowly, so give it a consistent 8 to 12 weeks before judging results.
Where to get it
Ready when you are. This link takes you to the official, verified source for this product.
Get Multi BeautyThe studies
See the research behind the science we point to.
Explore studiesThe blog
Plain-language reads on how it all fits together.
Read the blogOptimal nutrients are the definition of longevity
Long-term cell function depends on having what it needs, at the level it needs it, for as long as it needs it. That is the whole thesis behind everything we point you to here.
When you buy through our links, we earn a small commission — and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.