Solid, genuinely U-shaped — both deficiency and excess raise TSH and thyroid dysfunction rates, not a 'more is better' nutrient.
How it works
Build — incorporated directly onto tyrosine residues in thyroglobulin to construct the thyroid hormones T4 and T3
Sense — thyroid hormone acts as a master signaling molecule at nuclear receptors in nearly every cell type, setting metabolic tone body-wide
Transform — T4/T3 output regulates basal metabolic rate and mitochondrial oxidative capacity throughout the body
Process — adequate iodine and thyroid hormone status is required for normal fetal and childhood neurodevelopment and ongoing adult cognitive function
Form matters
The same nutrient can be made in very different forms — and a study done on one form does not automatically apply to another. Methylcobalamin is not cyanocobalamin; magnesium glycinate is not magnesium oxide; a whole-food extract is not the synthetic isolate that was studied. Two things decide whether what is in the bottle behaves like the research: the exact form, and independent lab verification (a Certificate of Analysis) that the form and dose on the label are truly what is inside. Without a COA, you are trusting a label, not the science.
Works well with
The science on Iodine
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