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When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
What it is
A standardized extract of red reishi mushroom (Ganoderma lucidum) that adds cracked-spore technology to free more of the mushroom's active compounds, delivering the triterpenes and polysaccharides reishi is known for (standardized to roughly 6% triterpenes and 13% polysaccharides). Taken as two capsules daily, it is used to support the body's normal, everyday immune signaling.
Why the evidence supports it
Reishi carries an unusually long traditional history in Eastern herbal medicine alongside a growing modern research base, and that honesty matters here: much of the finished-product and mechanistic evidence is still preclinical -- cell and animal work on how reishi compounds influence immune-cell activity -- rather than large human trials. Standardization and clean sourcing are what separate a meaningful reishi extract from a weak one, and this one is built for a high, verified level of actives. On that footing it is a reasonable, evidence-aware way to support the cell's Maintain function through normal immune-cell signaling, not a treatment for any condition.
What it supports
- Supports the body's normal, everyday immune signaling
- Supports a healthy inflammation response already within normal range
- Provides standardized reishi triterpenes and polysaccharides
- Complements a foundation of good sleep, nutrition, and minerals
Which function it supports
Ties to the cell's Maintain function via immune-cell signaling -- supporting the normal communication immune cells use to stay coordinated. This is signaling support only, not a treatment for any condition.
Learn the why behind this pillarHow it relates to your cells and mind
Every product here ties back to a specific job your body does. This one touches the functions below -- follow either link to see the mechanism in full, then dig into the studies.
What it is made of -- and the mechanisms behind it
Each ingredient acts on several of the body's functions. Taken together, this product touches these cell and mind functions -- follow any to see the mechanism in full.
The ingredients
Mechanisms drawn from our ingredient knowledge base (1 profiled ingredients). Structure and function only -- not a treatment claim.
What’s actually in it
Label revision 2014Transcribed from the manufacturer’s official Product Information Page, exactly as printed. Ingredient names that link open our research page for that ingredient, with the studies behind it.
| Amount per 2 capsules | Amount | % DV |
|---|---|---|
| Reishi Mushroom Powdered Extract with SporesGanoderma lucidum | 1000 mg | * |
- Servings per container:
- 30
Source: official Product Information Page . Amounts are the manufacturer’s, not ours. Structure and function only -- nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease.
The science on the ingredients
These studies are research on the ingredients and mechanisms in this product, not on the finished product itself, and they are shown for education. For this ingredient most of the published work is laboratory or animal research rather than human trials, so read it as biology worth knowing rather than proof of an effect in people. Nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease. Talk to your own provider about what is right for you.
- Ganoderma lucidum (reishi) cancer evidence, Cochrane reviewPubMed
Cochrane Database of Systematic Reviews · 2016
- Nutritional Profile and Health Benefits of Ganoderma lucidum "Lingzhi, Reishi, or Mannentake" as Functional Foods: Current Scenario and Future PerspectivesPubMed
2022
A review of Ganoderma lucidum as a functional food described accumulating evidence of antiviral activity against dengue, enterovirus 71 and COVID-19, while calling for more safety research.
- Cellular and physiological effects of Ganoderma lucidum (Reishi)PubMed
Mini reviews in medicinal chemistry · 2004
Review of Ganoderma lucidum (Reishi) effects on signaling pathways, describing immunostimulatory polysaccharides and triterpenes linked to its anticancer activity.
- Tres hongos que cuidan de tu salud: maitake, shiitake y reishiDOI
Con Evidencia · 2026
A consumer health article on maitake, shiitake and reishi mushrooms says lab and small human studies show promising but limited signals and that stronger human research is still needed.
- Ganoderma lucidum (reishi) as a functional nutraceutical in dogs: effects on metabolic biomarkers, digestive efficiency, and fecal qualityDOI
Romanian Journal of Veterinary Sciences · 2026
In dogs with metabolic imbalance, 45 days of Ganoderma lucidum powder was associated with lower alkaline phosphatase, bilirubin, triglycerides and cholesterol, plus improved protein digestibility and reduced fecal output.
- Reishi (Ganoderma lucidum): proprietà, integrazione, patologie trattate e ruolo su mTOR e AMPKDOI
LIFE Science Hub Journal of Science · 2026
This Reishi (Ganoderma lucidum) overview finds its best evidence in immunity, metabolism, and mTOR and AMPK pathways, with mixed results and limited direct clinical trials.
Mechanism of Ganoderma lucidum polysaccharides in the mangement of diabetes and its complicationsEstablishedSystematic review2026
This review found that Ganoderma lucidum polysaccharides showed protective effects against diabetes complications such as nephropathy, retinopathy and neuropathy, mostly from in vitro and animal studies.
Yu Xin; Xiwu Zhang; Di Han; Qichao Liang; Ling Kong; Yu Guan; Hui Sun; Chang Liu; Ying Han; Xiaoyu Wang; Xijun Wang
The Significance of a Mushroom Diet in the Prevention of OsteoporosisEmergingExpert review2026
Mushroom species including Lentinula edodes and Ganoderma lucidum contain vitamin D and minerals that support bone formation and may help prevent osteoporosis.
Małgorzata Cicha-Jeleń; Katarzyna Kała; Katarzyna Sułkowska-Ziaja; Bożena Muszyńska
From Remedy to Therapy: Confronting the Bioavailability Bottleneck in Ganoderma lucidum Translational ResearchEmergingExpert review2026
Ganoderma lucidum's bioactive triterpenoids and polysaccharides demonstrate in vitro potency, but no nanoformulation has advanced to human trials due to poor systemic bioavailability.
Yujie Qu; Xinyu Zhao; Hongxin Liu; Rutong Ren; Wenran Qu; Shili Wang; Guohua Ma
Ganoderma applanatum Polysaccharides in Obesity-Associated Dysglycaemia and Liver Injury: Gut-Liver Mechanisms and Translational GapsEmergingExpert review2026
Ganoderma applanatum polysaccharide preparations were associated with improved glucose tolerance, insulin sensitivity, and reduced liver injury markers in obesity-related metabolic disease.
Adamou Mfopa; Ibrahim Njimona; Célestin Mountchissi; Fabrice Mba Medou; Lum Abenwi Ambe; Kamgang René Moustapha; Emmanuel Eroume A Egom
The dual role of Ganoderma lucidum polysaccharides in cancer treatment: Meridian tropism-based direct inhibition and immune-mediated modulationEmergingExpert review2026
This review summarized evidence that Ganoderma lucidum polysaccharides directly suppress tumors and modulate immunity, and proposed linking organ-specific effects to traditional meridian theory.
Sang-Nguyen-Cao Phan; Wei-Jyun Hua; Li-Lan Liao; Zhi-Hu Lin; Diem-Ngoc-Hong Tran; Mei-Kuang Lu; Tung-Yi Lin
Anti-Inflammatory Potential of Ganoderma lucidum Triterpenes: A Systematic Review and Meta-Analysis of Preclinical EvidenceEmergingExpert review2026
A meta-analysis of 23 non-clinical studies found Ganoderma lucidum triterpenes significantly reduced nitric oxide, IL-6, and TNF-α levels in laboratory tests.
Rafaela Guedes Pozzobon; Renata Rutckeviski; Luíza Siqueira de Lima; Cláudia Sirlene Oliveira; Fhernanda Ribeiro Smiderle
Ganoderma lucidum as a Functional Bioactive Candidate for Glycemic Regulation: Mechanisms, Preclinical Evidence, and Clinical TranslationEmergingExpert review2026
Ganoderma lucidum has strong mechanistic plausibility for glycemic regulation but insufficient clinical evidence, as its largest randomized trial in type 2 diabetes showed no significant glycemic benefit.
Bogdan Florea; Doru Morar; Corina Marina Kracunovic; Simina Velescu; Vlad Iorgoni; Paula Nistor; Janos Degi; Ionica Iancu; Maria-Larisa Ardelean Rusu; Romeo Teodor Cristina; Alexandra Pocinoc; Eugenia Dumitrescu
NARRATIVE REVIEW : METODE EKSTRAKSI GANODERMA LUCIDUM DAN EFEKTIVITASNYAEmergingExpert review2026
This narrative review found that extraction method, solvent, temperature and duration substantially affect the yield and stability of Ganoderma lucidum's bioactive compounds, with standardization still lacking across studies.
Meinanda Grabilia; Diana Laila Rahmatillah; Kashif Khan -- INDONESIA NATURAL RESEARCH PHARMACEUTICAL JOURNAL
The Gut -- Brain Axis in Ganoderma lucidum’s Antidepressant Effects in Cancer Comorbidity: A ReviewEmergingExpert review2026
In animal models, Ganoderma lucidum reduced depressive-like behaviour, with gut microbiota modulation proposed as the mechanism, though human depression outcomes in cancer patients were rarely assessed.
Xia-Ying Du; Fan Bu; Zhi‐Qiang Ling -- Journal of Nutrition
Ganoderma lucidum spore powder enhances IFN-α-mediated antiviral capacity of COVID-19 vaccine boosters revealed by single-cell multi-omics sequencingEmergingPrimary research (design unspecified)2026
In participants with moderate baseline immunity, Ganoderma lucidum spore powder significantly enhanced neutralizing antibody inhibition 90 days after a COVID-19 vaccine booster, with ganoderic acid H identified as the active compound.
Anyao Li; Xiaoyan Lu; Rongfang Guo; Wenbo Guo; Penghui Yang; He Lou; Jie Chen; Enshan Huang; Ronghua Zhang; Hanbo Wang; Jihong Yang; Zhenhao Li; Xiaohui Fan
Protective effects of Ganoderma lucidum polysaccharide peptides against cisplatin-induced toxicity.2026
In animal and cell models, Ganoderma lucidum (reishi) polysaccharide peptides reduced markers of oxidative stress, inflammation, and cell death associated with cisplatin-induced organ toxicity.
Hou Z; Ji W; Yang S; Zhang Y; Yang T; Wang L; Luo H; Lin D; Yang B; Chen X; Fang H -- Journal of ethnopharmacology
The Ganoderma atrum Polysaccharide PSG-1 Attenuates Acrylamide-Induced Hepatotoxicity by Modulating the FXR-FGF15-Mediated Gut-Liver AxisEmergingPrimary research (design unspecified)2026
Ganoderma atrum polysaccharide PSG-1 attenuated acrylamide-induced hepatotoxicity in mice by restoring intestinal dysbiosis, enhancing antioxidant defense, and reactivating FXR-FGF15-mediated bile acid signaling.
Shiyu Chen; Chunchao Nie; Yuting Wang; Ziyan Guo; Kaichang Zhao; Qiang Yu; Jianhua Xie; Yi Chen
Effects of Biochar on Physiological and Biochemical Characteristics of Ganoderma lingzhi (Lingzhi) During Cultivation.2026
A cultivation study found that adding biochar to the growth substrate increased Ganoderma lingzhi (reishi) mycelial growth rate and extracellular enzyme activity while decreasing mycelial protein levels.
Ning Z; Jiang Y; Duan X; Zhang Y; Zhang B; Hua S; Li X; Wu J -- Journal of basic microbiology
A Triterpenoid-Enriched GLE70 Fraction From Ganoderma lingzhi Ameliorates Alcoholic Liver Disease via Multi-Target RegulationEmergingPrimary research (design unspecified)2026
Ganoderma lingzhi triterpenoids reduce alcoholic liver disease through AKT1 activation, TNF-α reduction, and improved lipid and antioxidant metabolism.
Yanjun Chen; Wenjia Li; Shiyi Ye; Jiaxue Li; Xiaobing Song; Qianli Ma; Ping Chen; Biying Zhang
Microwave-Assisted Extraction Optimization, Solubility, and Bioactivity Evaluation of Polysaccharides from Broken Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Spore Powder.2026
Researchers optimized microwave-assisted extraction of polysaccharides from broken Ganoderma lucidum (reishi) spore powder, finding in vitro antioxidant and hypouricemic activity under optimal extraction conditions.
Liu Y; Guo LG; Dong X; Wang S; Xu H; Zhou H -- International journal of medicinal mushrooms
Integrated Foodomics Reveals Gut Microbiota-Metabolite-Gene Interactions Associated with the Immunoprotective Effects of Ganoderma lucidum Polysaccharide PeptideEmergingPrimary research (design unspecified)2026
Ganoderma lucidum polysaccharide-peptide restored immune organ function, enhanced lymphocyte proliferation, and rebalanced pro- and anti-inflammatory responses in cyclophosphamide-immunosuppressed mice.
Jing Xie; Zilong An; Dongmei Lin; Jing Li; Shuqi Yu; Mazurenko Ihor; Zhanxi Lin
Mushrooms as potent autophagy modulators in cancer therapy: Current evidence and therapeutic prospects.2026
Over 18 mushroom species and 28 bioactive compounds, including Ganoderic acid and cordycepin, were reviewed for their ability to modulate autophagy across 15 cancer types including colorectal, lung, breast, and liver cancer.
Hasan MM; Azme E; Alam R; Mamun MJI; Chowdhury MT; Rasel MH; Momen MSH; Hoque N; Ekram MEH; Eshaque NH; Ahmed S; Tipu MTR; Juthi SS; Kabir MF; Ullah A; Ali ML; Hossen SMM; Chung HJ -- Cancer pathogenesis and therapy
Solid-State Fermentation of Jatropha curcas Cake by Pleurotus ostreatus or Ganoderma lucidum Mycelium to Determine Multi-BioactivitiesEmergingPrimary research (design unspecified)2026
Solid-state fermentation of Jatropha cake with Ganoderma lucidum released peptides with antidiabetic, antihypertensive, and antioxidant activities.
Enrique Javier Olloqui; Emmanuel Pérez-Escalante; Raúl Velasco-Azorsa; Carlos Gutierrez; Juan Carlos Moreno-Seceña; Daniel Martínez-Carrera
Physicochemical profiles and antioxidant capacities of lingzhi (Ganoderma lingzhi) polysaccharides under different extraction regimes.2026
Crude Ganoderma lingzhi (reishi) polysaccharide extract showed stronger DPPH and hydroxyl radical scavenging activity than purified fractions GLP1 and GLP2, which differed in molecular weight and monosaccharide composition.
Liu H; Hua J; Xie J; Zhang B; Hua S; Li X; Duan X -- Natural product research
Cosmetic potential of Ganoderma lucidum (Reishi) extract in a topical cream formulationEmergingPrimary research (design unspecified)2026
Ganoderma lucidum extract demonstrated superior antioxidant and tyrosinase-inhibitory activity compared with argireline peptide and α-arbutin in a stable topical cream.
Sibel Dikmen Kucuk; Paul Jabet; Anthony Groso; Guillaume Collet; Richard Daniellou; Beste Karadeniz
Phytochemical Profiling and Bioactivity Evaluation of Ganoderma lucidum (Reishi Mushroom) Fractions: In Vitro Antioxidant, Antimicrobial, and Antidiabetic Activities.2026
Chromatographic fractionation of Ganoderma lucidum (reishi) identified 46 bioactive compounds, with distinct fractions showing the strongest antioxidant activity, antibacterial activity against E. coli and K. pneumoniae, and selective alpha-amylase versus alpha-glucosidase enzyme inhibition.
Shehzadi N; Khan S; Degennaro L; D'Arienzo G; Mehmood N; Chaudhary A; Afzal M; Argentieri MP -- Metabolites
Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized miceEmergingPrimary research (design unspecified)2026
In ovariectomized mice modeling menopause, Ganoderma lucidum polysaccharides lowered serum total and LDL cholesterol, reduced liver fat, altered hepatic gene expression, and shifted the gut microbiota composition.
Xin Jin; Xuan Liu; Yun-Juan Wang; Zi-Li Lei; Yan-Hong Yang
[Screening of potential bioactive constituents in wall-broken Ganoderma lucidum spore powder for promoting ulcer healing]EmergingPrimary research (design unspecified)2026
Ganoderic acid A and G from wall-broken Ganoderma lucidum spore powder enhanced collagen deposition and angiogenesis, accelerating oral ulcer healing in a rat model.
Juan Liu; Jiaqi Wang; Yuan Li; Yuyi Cong; Xiaobing Guan
The Medicinal Mushroom Ganoderma: A Review of Systematics, Phylogeny, and Metabolomic InsightsEmergingPrimary research (design unspecified)2026
ITS sequencing and metabolomics profiling improve Ganoderma species identification and quality control compared to morphology alone, with significant geographic data gaps in Africa.
Gideon Adotey; Abraham Quarcoo; Mohammed Ahmed Gedel; Paul Yerenkyi; Phyllis Otu; Abraham Kwabena Anang; Laud Kenneth Okine; W.S.K. Gbewonyo; John C. Holliday; Vincent C. Lombardi -- Journal of Fungi
Balanced by design -- we show supporting and contradicting findings. Search all studies
If you have had labs done
These are lab markers where this product's ingredients have measured evidence in our citation library. This is not a claim that the product will change your results -- the research attaches to the ingredient, and what a marker means depends on the whole picture. Each one links to its full entry, including what typically moves it and how to read it.
- Prostate-Specific Antigen (PSA) Total, Free & Percent Freeemerging evidence
via Reishi · 5 studies, 3 in people
What people often notice when this marker sits outside the usual range
Higher: Frequently NOTHING -- which is the entire reason PSA is measured rather than waited for.
Lower: No symptoms. ⚠️ Note that finasteride and dutasteride roughly HALVE PSA -- a result on either must be doubled to be interpreted, and forgetting this hides real findings.
Lab results are interpreted by a qualified clinician who knows your history. Nothing here diagnoses anything or replaces that conversation.
No product works in isolation
Every cell function above -- Sense, Exchange, Transform, Build, Maintain, Adapt -- needs the same broad base of optimal micronutrient levels running underneath it, all the time. ReishiMax GLp is not a stand-alone fix; it is one piece that plugs into that larger system. The foundation comes first, and this supports it.
Stacks well with
Pick your goal -- here is what ReishiMax GLp pairs with for each. Nothing works in isolation; these share the same systems.
For Immune
For Energy & Mitochondria
For Gut Health
Foundational, or targeted?
Not everything in the shop is meant to be taken forever. Some products here are foundational -- a daily nutrient base built for long-term, ongoing use. Others are targeted -- shorter-term support for a specific season, not a lifelong habit. If you are not sure which one this is, that is a fair question to ask us before you buy.
Learn more, on your terms
Do not take our word for it -- go read. Each topic below opens a pre-loaded search so you can explore the nutrient, the mechanism, or the device for yourself.
Search the full studies libraryHow to use it
Take with water on the schedule on the label. Current bottle directions vary, so follow the label you have.
Where to get it
Ready when you are. This link takes you to the official, verified source for this product.
Get ReishiMax GLpThe studies
See the research behind the science we point to.
Explore studiesThe blog
Plain-language reads on how it all fits together.
Read the blogOptimal nutrients are the definition of longevity
Long-term cell function depends on having what it needs, at the level it needs it, for as long as it needs it. That is the whole thesis behind everything we point you to here.
When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
ReishiMax GLp is a standardized reishi mushroom extract with cracked spores, delivering the triterpenes and polysaccharides the mushroom is known for. Reishi is a long-used botanical in Eastern herbal traditions, taken here to support the body's normal immune signaling. It fits people who want grounded, everyday immune-signaling support.
FAQ
What does ReishiMax GLp support?
It supports the body's normal, everyday immune signaling and a healthy inflammation response already within normal range, provides standardized reishi triterpenes and polysaccharides, and complements a foundation of good sleep, nutrition, and minerals.
How do I take it?
Take with water on the schedule on the label. Current bottle directions vary, so follow the label you have.
What makes it different?
Reishi has a deep traditional history and a real, if early, research base, so it is presented as everyday immune-signaling support rather than anything stronger. Sourcing and standardization matter here.