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When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
What it is
A standardized extract of red reishi mushroom (Ganoderma lucidum) that adds cracked-spore technology to free more of the mushroom's active compounds, delivering the triterpenes and polysaccharides reishi is known for (standardized to roughly 6% triterpenes and 13% polysaccharides). Taken as two capsules daily, it is used to support the body's normal, everyday immune signaling.
Why the evidence supports it
Reishi carries an unusually long traditional history in Eastern herbal medicine alongside a growing modern research base, and that honesty matters here: much of the finished-product and mechanistic evidence is still preclinical -- cell and animal work on how reishi compounds influence immune-cell activity -- rather than large human trials. Standardization and clean sourcing are what separate a meaningful reishi extract from a weak one, and this one is built for a high, verified level of actives. On that footing it is a reasonable, evidence-aware way to support the cell's Maintain function through normal immune-cell signaling, not a treatment for any condition.
What it supports
- Supports the body's normal, everyday immune signaling
- Supports a healthy inflammation response already within normal range
- Provides standardized reishi triterpenes and polysaccharides
- Complements a foundation of good sleep, nutrition, and minerals
Which function it supports
Ties to the cell's Maintain function via immune-cell signaling -- supporting the normal communication immune cells use to stay coordinated. This is signaling support only, not a treatment for any condition.
Learn the why behind this pillarHow it relates to your cells and mind
Every product here ties back to a specific job your body does. This one touches the functions below -- follow either link to see the mechanism in full, then dig into the studies.
What it is made of -- and the mechanisms behind it
Each ingredient acts on several of the body's functions. Taken together, this product touches these cell and mind functions -- follow any to see the mechanism in full.
The ingredients
Mechanisms drawn from our ingredient knowledge base (1 profiled ingredients). Structure and function only -- not a treatment claim.
What’s actually in it
Label revision 2014Transcribed from the manufacturer’s official Product Information Page, exactly as printed. Ingredient names that link open our research page for that ingredient, with the studies behind it.
| Amount per 2 capsules | Amount | % DV |
|---|---|---|
| Reishi Mushroom Powdered Extract with SporesGanoderma lucidum | 1000 mg | * |
- Servings per container:
- 30
Source: official Product Information Page . Amounts are the manufacturer’s, not ours. Structure and function only -- nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease.
The science on the ingredients
These studies are research on the ingredients and mechanisms in this product, not on the finished product itself, and they are shown for education. For this ingredient most of the published work is laboratory or animal research rather than human trials, so read it as biology worth knowing rather than proof of an effect in people. Nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease. Talk to your own provider about what is right for you.
- Ganoderma lucidum (reishi) cancer evidence, Cochrane review
Cochrane Database of Systematic Reviews · 2016
- Health Benefits of Ganoderma lucidum (Reishi) Supplementation for Athletes: A Narrative Review
Quality in Sport · 2026
A narrative review of Ganoderma lucidum in athletes found a few small human studies reporting improved maximal oxygen uptake and muscle strength, but judged the evidence too limited for supplementation recommendations.
- Phytochemical Profiling and Bioactivity Evaluation of Ganoderma lucidum (Reishi Mushroom) Fractions: In Vitro Antioxidant, Antimicrobial, and Antidiabetic Activities.
Metabolites · 2026
Chromatographic fractionation of Ganoderma lucidum (reishi) identified 46 bioactive compounds, with distinct fractions showing the strongest antioxidant activity, antibacterial activity against E. coli and K. pneumoniae, and selective alpha-amylase versus alpha-glucosidase enzyme inhibition.
- Effects of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Triterpene on Motor and Spatial Learning Disorders in 5xFAD Mice
International Journal of Medicinal Mushrooms · 2025
In 5xFAD mice, 0.5 g/kg Ganoderma lucidum triterpenoids decreased escape latency and limb errors, increased platform crossings and movement time, and lowered glutamate content compared with untreated 5xFAD mice.
- Reishi Mushroom (Ganoderma lucidum): pharmacology of a potent healer in traditional Chinese medicine.
Natural product research · 2025
A review of Ganoderma lucidum (Reishi) describes over 400 bioactive compounds, mainly triterpenoids and polysaccharides, associated with immunomodulatory, antioxidant, antidiabetic, and neuroprotective properties, plus emerging anti-obesity and alopecia research.
- Strategies to Increase the Production of Triterpene Acids in Ligzhi or Reishi Medicinal Mushroom (Ganoderma lucidum, Agaricomycetes): A Review
International Journal of Medicinal Mushrooms · 2024
A review of Ganoderma lucidum cultivation identifies fermentation conditions, elicitors, genetic engineering, and mutagenesis as strategies to increase low yields of ganoderic acid, the mushroom's main bioactive compound.
Biologic activity of spores and dried powder from Ganoderma lucidum for the inhibition of highly invasive human breast and prostate cancer cells.2003
In lab tests on human breast and prostate cancer cells, some reishi mushroom samples strongly blocked cell migration and a related inflammation pathway, but activity varied widely and did not track with sample purity.
Sliva D; Sedlak M; Slivova V; Valachovicova T; Lloyd FP Jr; Ho NW -- Journal of alternative and complementary medicine (New York, N.Y.)
Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities.2002
A fucose-containing sugar-protein fraction from reishi mushroom stimulated immune cell growth and boosted cytokine production, including IL-1, IL-2 and interferon-gamma, in cultured mouse spleen cells.
Wang YY; Khoo KH; Chen ST; Lin CC; Wong CH; Lin CH -- Bioorganic & medicinal chemistry
The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells.1992
In laboratory experiments, a polysaccharide extracted from the medicinal mushroom Ganoderma lucidum did not directly affect leukemia cell growth, but signaling molecules from immune cells exposed to it caused the leukemia cells to mature into normal monocyte-like cells.
Lieu CW; Lee SS; Wang SY -- Anticancer research
The Nutritional Significance of Ganoderma lucidum on Human Health: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials,Meta-analysis2025
Pooled 17 RCTs/971 participants; significant reductions only in BMI, creatinine, glutathione peroxidase, heart rate; no significant effect on body fat, waist circumference, blood pressure, fasting glucose, lipid profile, inflammatory markers, or liver enzymes. PMC12160064.
Jafari et al. -- Food Science & Nutrition
A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Reishi Mushroom (Ganoderma lucidum), Stinging Nettle (Urtica dioica), and Epimedium (Epimedium sagittatum).ContestedRandomized controlled trial2021
In a small placebo-controlled crossover trial of 29 men with Gulf War Illness, epimedium showed no significant improvement in symptoms at either the lower or higher dose.
Younger J; Donovan EK; Hodgin KS; Ness TJ -- International journal of environmental research and public health
Randomized Clinical Trial for the Evaluation of Immune Modulation by Yogurt Enriched with beta-Glucans from Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) in Children from Medellin ColombiaRandomized controlled trial2018
A randomized clinical trial in children found that yogurt enriched with reishi mushroom beta-glucans was associated with markers of immune modulation compared with standard yogurt.
Study authors -- International Journal of Medicinal Mushrooms
Ganoderma lucidum Effects on Mood and Health-Related Quality of Life in Women with FibromyalgiaContestedRandomized controlled trial2020
Six weeks of Ganoderma lucidum (reishi) supplementation showed no statistically significant improvement in mood or quality-of-life scores compared with placebo in women with fibromyalgia.
Collado Mateo D, Adsuar JC, Olivares PR, et al. -- Healthcare (Basel)
A double-blind, randomised, placebo-controlled trial of Ganoderma lucidum for the treatment of cardiovascular risk factors of metabolic syndrome,Randomized controlled trial2016
Klupp NL et al., "A double-blind, randomised, placebo-controlled trial of Ganoderma lucidum for the treatment of cardiovascular risk factors of metabolic syndrome," Scientific Reports, 2016
Klupp NL et al. -- Scientific Reports
Evaluation of Immune Modulation by beta-1,3;1,6 D-Glucan Derived from Ganoderma lucidum in Healthy Adult Volunteers, A Randomized Controlled Trial.Randomized controlled trial
Not a study. This record is a truncated fragment ('placebo. PMC9914031.') with no title, finding or method recoverable from the stored text.
Shiu-Nan Chen; Fan-Hua Nan; Ming-Wei Liu; Min-Feng Yang; Ya-Chih Chang; Sherwin Chen -- 84-day dosing significantly increased CD3+/CD4+/CD8+ T-lymphocytes, improved CD4/CD8 ratio, increased NK cell counts vs
Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidumEmergingExpert review2005
This review describes how Ganoderma lucidum polysaccharides trigger receptor-mediated signaling cascades that upregulate cytokine and immune-cell gene programs in laboratory models.
Lin ZB -- Journal of Pharmacological Sciences
Ganoderma lucidum spore oil with Ganoderma lucidum and Ganoderma sinense extracts (G2SO) shows antitumor and Immunomodulatory effects in miceEmerging2026
In tumour-bearing BALB/c mice, a Ganoderma lucidum spore oil and extract formulation inhibited 4T1 tumours by 35.3% and produced small increases in NK cell cytotoxicity and macrophage phagocytosis.
Ricardo A Wu-Chen; Chongxian Li; Changhui Wu; Kun Zhang; Liling Hong; Zucheng Ye; Cainan Wang; Jiancheng Xu; Xueyan Liu; Ye Li
Mushrooms as potent autophagy modulators in cancer therapy: Current evidence and therapeutic prospects.2026
Over 18 mushroom species and 28 bioactive compounds, including Ganoderic acid and cordycepin, were reviewed for their ability to modulate autophagy across 15 cancer types including colorectal, lung, breast, and liver cancer.
Hasan MM; Azme E; Alam R; Mamun MJI; Chowdhury MT; Rasel MH; Momen MSH; Hoque N; Ekram MEH; Eshaque NH; Ahmed S; Tipu MTR; Juthi SS; Kabir MF; Ullah A; Ali ML; Hossen SMM; Chung HJ -- Cancer pathogenesis and therapy
Health Benefits of Ganoderma lucidum (Reishi) Supplementation for Athletes: A Narrative ReviewEmerging2026
A narrative review of Ganoderma lucidum in athletes found a few small human studies reporting improved maximal oxygen uptake and muscle strength, but judged the evidence too limited for supplementation recommendations.
Kacper Szada-Borzyszkowski; Konstancja Owczarenko -- Quality in Sport
Microwave-Assisted Extraction Optimization, Solubility, and Bioactivity Evaluation of Polysaccharides from Broken Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Spore Powder.2026
Researchers optimized microwave-assisted extraction of polysaccharides from broken Ganoderma lucidum (reishi) spore powder, finding in vitro antioxidant and hypouricemic activity under optimal extraction conditions.
Liu Y; Guo LG; Dong X; Wang S; Xu H; Zhou H -- International journal of medicinal mushrooms
Characterization of a New Biocomposite Based on Bioactive Compounds from Ganoderma lucidum and Jellyfish Collagen Destined for In Vitro Evaluation of Antitumor Effects in the Oral CavityEmerging2026
A biocomposite of Ganoderma lucidum extract in Rhizostoma pulmo collagen preserved type I collagen structure, showed stronger antioxidant and antimicrobial activity than collagen alone, and dose-dependently reduced viability and migration of two oral carcinoma cell lines.
Pascale C; Burcea A; Bogdan-Andreescu CF; Cadar E; Popescu A; Negreanu-Pirjol T; Busuricu F; Pesterau AM; Rosca AC; Sirbu R -- Pharmaceuticals (Basel, Switzerland)
Effects of Biochar on Physiological and Biochemical Characteristics of Ganoderma lingzhi (Lingzhi) During Cultivation.2026
A cultivation study found that adding biochar to the growth substrate increased Ganoderma lingzhi (reishi) mycelial growth rate and extracellular enzyme activity while decreasing mycelial protein levels.
Ning Z; Jiang Y; Duan X; Zhang Y; Zhang B; Hua S; Li X; Wu J -- Journal of basic microbiology
Heat stress-induced degradation of glutamine synthetase rebalances central carbon-nitrogen metabolism and promotes thermotolerance in <i>Ganoderma lucidum</i>Emerging2026
Silencing glutamine synthetase in Ganoderma lucidum cut heat-induced growth inhibition from 20.7 percent to 9.71 percent and raised alpha-ketoglutarate, while heat stress lowered the enzyme by 29 percent via proteasomal degradation.
Jinjin Qiao; Huajun Li; Yuzhen Yang; Yanqiu Li; Shangshang Zhang; Mingwen Zhao; Jing Zhu
Protective effects of Ganoderma lucidum polysaccharide peptides against cisplatin-induced toxicity.2026
In animal and cell models, Ganoderma lucidum (reishi) polysaccharide peptides reduced markers of oxidative stress, inflammation, and cell death associated with cisplatin-induced organ toxicity.
Hou Z; Ji W; Yang S; Zhang Y; Yang T; Wang L; Luo H; Lin D; Yang B; Chen X; Fang H -- Journal of ethnopharmacology
Ganoderma lucidum spore powder enhances IFN-α-mediated antiviral capacity of COVID-19 vaccine boosters revealed by single-cell multi-omics sequencingEmergingPrimary research (design unspecified)2026
In participants with moderate baseline immunity, Ganoderma lucidum spore powder significantly enhanced neutralizing antibody inhibition 90 days after a COVID-19 vaccine booster, with ganoderic acid H identified as the active compound.
Anyao Li; Xiaoyan Lu; Rongfang Guo; Wenbo Guo; Penghui Yang; He Lou; Jie Chen; Enshan Huang; Ronghua Zhang; Hanbo Wang; Jihong Yang; Zhenhao Li; Xiaohui Fan
Physicochemical profiles and antioxidant capacities of lingzhi (Ganoderma lingzhi) polysaccharides under different extraction regimes.2026
Crude Ganoderma lingzhi (reishi) polysaccharide extract showed stronger DPPH and hydroxyl radical scavenging activity than purified fractions GLP1 and GLP2, which differed in molecular weight and monosaccharide composition.
Liu H; Hua J; Xie J; Zhang B; Hua S; Li X; Duan X -- Natural product research
Preparation and Bioactivity Evaluation of Novel Dihydrotanshinone I Derivatives via Biotransformation by <i>Ganoderma lingzhi</i>Emerging2026
Biotransforming dihydrotanshinone I with Ganoderma lingzhi yielded seven products including five novel compounds, with one inhibiting nitric oxide in stimulated macrophages and another protecting neuronal cells from peroxide stress.
Yixuan Wang; Wenjun Xu; Shiting Qiu; Siya Ying; Ka Hong Wong; Tianpeng Yin; Siwen Yuan; Kun Feng
Phytochemical Profiling and Bioactivity Evaluation of Ganoderma lucidum (Reishi Mushroom) Fractions: In Vitro Antioxidant, Antimicrobial, and Antidiabetic Activities.2026
Chromatographic fractionation of Ganoderma lucidum (reishi) identified 46 bioactive compounds, with distinct fractions showing the strongest antioxidant activity, antibacterial activity against E. coli and K. pneumoniae, and selective alpha-amylase versus alpha-glucosidase enzyme inhibition.
Shehzadi N; Khan S; Degennaro L; D'Arienzo G; Mehmood N; Chaudhary A; Afzal M; Argentieri MP -- Metabolites
The Nutritional Significance of <i>Ganoderma lucidum</i> on Human Health: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical TrialsEmerging2025
A meta-analysis of 17 randomised trials with 971 participants found Ganoderma lucidum supplementation lowered BMI by 0.43, creatinine and heart rate and raised glutathione peroxidase, with very low certainty evidence.
Ali Jafari; Helia Mardani; Zahra Mirzaei Fashtali; Bahareh Arghavan
Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action.2025
Ganoderma (reishi) mushroom's polysaccharides, triterpenoids, and phenolic compounds showed antimicrobial activity by disrupting bacterial cell walls and membranes and inhibiting key microbial enzymes.
Karunarathna SC; Patabendige NM; Hapuarachchi KK; Promputtha I -- Frontiers in cellular and infection microbiology
Balanced by design -- we show supporting and contradicting findings. Search all studies
If you have had labs done
These are lab markers where this product's ingredients have measured evidence in our citation library. This is not a claim that the product will change your results -- the research attaches to the ingredient, and what a marker means depends on the whole picture. Each one links to its full entry, including what typically moves it and how to read it.
- Prostate-Specific Antigen (PSA) Total, Free & Percent Freeemerging evidence
via Reishi · 5 studies, 3 in people
What people often notice when this marker sits outside the usual range
Higher: Frequently NOTHING -- which is the entire reason PSA is measured rather than waited for.
Lower: No symptoms. ⚠️ Note that finasteride and dutasteride roughly HALVE PSA -- a result on either must be doubled to be interpreted, and forgetting this hides real findings.
Lab results are interpreted by a qualified clinician who knows your history. Nothing here diagnoses anything or replaces that conversation.
No product works in isolation
Every cell function above -- Sense, Exchange, Transform, Build, Maintain, Adapt -- needs the same broad base of optimal micronutrient levels running underneath it, all the time. ReishiMax GLp is not a stand-alone fix; it is one piece that plugs into that larger system. The foundation comes first, and this supports it.
Stacks well with
Pick your goal -- here is what ReishiMax GLp pairs with for each. Nothing works in isolation; these share the same systems.
For Immune
For Energy & Mitochondria
For Gut Health
Foundational, or targeted?
Not everything in the shop is meant to be taken forever. Some products here are foundational -- a daily nutrient base built for long-term, ongoing use. Others are targeted -- shorter-term support for a specific season, not a lifelong habit. If you are not sure which one this is, that is a fair question to ask us before you buy.
Learn more, on your terms
Do not take our word for it -- go read. Each topic below opens a pre-loaded search so you can explore the nutrient, the mechanism, or the device for yourself.
Search the full studies libraryHow to use it
Take with water on the schedule the brand suggests. Current bottle directions vary, so follow the label you have.
Where to get it
Ready when you are. This link takes you to the official, verified source for this product.
Get ReishiMax GLpThe studies
See the research behind the science we point to.
Explore studiesThe blog
Plain-language reads on how it all fits together.
Read the blogOptimal nutrients are the definition of longevity
Long-term cell function depends on having what it needs, at the level it needs it, for as long as it needs it. That is the whole thesis behind everything we point you to here.
When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
ReishiMax GLp is a standardized reishi mushroom extract with cracked spores, delivering the triterpenes and polysaccharides the mushroom is known for. Reishi is a long-used botanical in Eastern herbal traditions, taken here to support the body's normal immune signaling. It fits people who want grounded, everyday immune-signaling support.
FAQ
What does ReishiMax GLp support?
It supports the body's normal, everyday immune signaling and a healthy inflammation response already within normal range, provides standardized reishi triterpenes and polysaccharides, and complements a foundation of good sleep, nutrition, and minerals.
How do I take it?
Take with water on the schedule the brand suggests. Current bottle directions vary, so follow the label you have.
What makes it different?
Reishi has a deep traditional history and a real, if early, research base, so it is presented as everyday immune-signaling support rather than anything stronger. Sourcing and standardization matter here.