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When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
What it is
This is the daytime engine of ageLOC R2 -- six morning capsules of cordyceps Cs-4, Panax ginseng, and pomegranate that work the epigenetics of energy. R2 is a two-part system: R2 Night runs the overnight genetic detox, and R2 Day targets the other side -- the gene-expression patterns behind cellular ENERGY production, right where the mitochondria turn food into usable fuel. The daytime vitality that rides on that engine is the point: physical vigor, mental acuity, and sexual health.
Why the evidence supports it
The honest frame, straight from the product's own science, is energy -- not detox (that is R2 Night's job). The ageLOC method behind R2 compared age-related gene-expression patterns and screened natural compounds for the ones that shifted the cellular-energy pattern toward a more youthful state, selecting cordyceps, ginseng, and pomegranate on that basis -- and the ageLOC Vitality research it grew from mapped that gene modulation across three tissues at once: brain, heart, and skeletal muscle (the specific gene count is Nu Skin's own figure). Each ingredient carries its own human evidence for that daytime story: cordyceps Cs-4 for exercise capacity and oxygen use (VO2max), Panax ginseng for energy and fatigue, mental acuity, and sexual vitality in both men and women, and pomegranate for mitochondrial support. Graded honestly, most of that ingredient evidence is emerging rather than settled, and the finished-formula gene-expression claim is emerging -- so this supports the cell's Transform function and daytime vitality, it does not treat fatigue or any condition.
What it supports
- Supports cellular energy production and mitochondrial function
- Supports daytime physical vigor and stamina
- Supports mental acuity and everyday cognition
- Supports healthy libido and sexual vitality in men and women
Which function it supports
Ties to the cell's Transform function -- supporting youthful gene expression for cellular energy production (the mitochondria) across brain, heart, and skeletal muscle, and the daytime vitality that depends on it. NRF2/purification is R2 Night's role, not this one.
Learn the why behind this pillarHow it relates to your cells and mind
Every product here ties back to a specific job your body does. This one touches the functions below -- follow either link to see the mechanism in full, then dig into the studies.
What it is made of -- and the mechanisms behind it
Each ingredient acts on several of the body's functions. Taken together, this product touches these cell and mind functions -- follow any to see the mechanism in full.
The ingredients
Mechanisms drawn from our ingredient knowledge base (3 profiled ingredients). Structure and function only -- not a treatment claim.
What’s actually in it
Label revision US Supplement Facts image from the US product page, read 2026-09-11Transcribed from the manufacturer’s official Product Information Page, exactly as printed.
| Amount per 6 capsules | Amount | % DV |
|---|---|---|
| Calories | 10 | |
| Total Carbohydrates | 2 g | 1%** |
| Dietary Fiber | <1 g | 2%** |
| Protein | 1 g | |
| ageLOC Recharge BlendCordyceps Cs-4 mushroom mycelia (Paecilomyces hepiali), pomegranate (Punica granatum) fruit extract, Pharmanex Asian ginseng Rb1 (Panax ginseng) root extract | 2270 mg | * |
- Servings per container:
- 30
US panel. The only PIP linked from this product's page is the SINGAPORE edition (ageLOC-R2-PIP-SG.pdf, nuskin.com.sg in the footer), so the US Supplement Facts image is the source here. If a US PIP appears, re-verify against it.
Source: official Product Information Page . Amounts are the manufacturer’s, not ours. Structure and function only -- nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease.
The science on the ingredients
If you have had labs done
These are lab markers where this product's ingredients have measured evidence in our citation library. This is not a claim that the product will change your results -- the research attaches to the ingredient, and what a marker means depends on the whole picture. Each one links to its full entry, including what typically moves it and how to read it.
- Fecal Calprotectinemerging evidence
via Pomegranate extract · 1 studies, 1 in people
A 12-week juice intervention with a modulatory effect on the relevant transcriptional profile.
What people often notice when this marker sits outside the usual range
Higher: Diarrhoea, often with urgency; blood or mucus in stool.
Lab results are interpreted by a qualified clinician who knows your history. Nothing here diagnoses anything or replaces that conversation.
No product works in isolation
Every cell function above -- Sense, Exchange, Transform, Build, Maintain, Adapt -- needs the same broad base of optimal micronutrient levels running underneath it, all the time. ageLOC R2 Day is not a stand-alone fix; it is one piece that plugs into that larger system. The foundation comes first, and this supports it.
Stacks well with
Pick your goal -- here is what ageLOC R2 Day pairs with for each. Nothing works in isolation; these share the same systems.
For Epigenetics
For Energy & Mitochondria
For Mood & Hormones
For Gut Health
Foundational, or targeted?
Not everything in the shop is meant to be taken forever. Some products here are foundational -- a daily nutrient base built for long-term, ongoing use. Others are targeted -- shorter-term support for a specific season, not a lifelong habit. If you are not sure which one this is, that is a fair question to ask us before you buy.
Learn more, on your terms
Do not take our word for it -- go read. Each topic below opens a pre-loaded search so you can explore the nutrient, the mechanism, or the device for yourself.
Search the full studies libraryHow to use it
Take six capsules in the morning, with or without food, and pair with R2 Night in the evening -- the two halves are designed to be used together. Follow the current label.
Where to get it
Ready when you are. This link takes you to the official, verified source for this product.
Get ageLOC R2 DayThe studies
See the research behind the science we point to.
Explore studiesThe blog
Plain-language reads on how it all fits together.
Read the blogOptimal nutrients are the definition of longevity
Long-term cell function depends on having what it needs, at the level it needs it, for as long as it needs it. That is the whole thesis behind everything we point you to here.
When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
ageLOC R2 is a two-part daily system built to support the cell's own renewal and energy pathways as we age. One part leans toward daytime purification support, the other toward overnight energy and renewal support. It fits people who want a thoughtfully timed longevity routine rather than one generic pill.
FAQ
What does ageLOC R2 support?
It supports the cell's natural renewal processes, the body's normal antioxidant defenses, healthy cellular energy production, and healthy cellular aging over time. It supports the body's own renewal; it does not reverse aging or reset genes.
How do I take it?
Take the daytime portion in the morning and the evening portion at night, each with water, following the pack layout. The morning-and-night rhythm is the whole point, so keep both consistent.
What makes it different?
It is two formulas timed to the body's day-and-night rhythm, aimed at supporting the cell's own maintenance machinery rather than a single all-day dose.