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What it is
A purified fulvic and humic mineral complex sourced from mountain rock, naturally rich in fulvic acid, dibenzo-alpha-pyrones, and a wide spread of trace minerals. These compounds are studied for their role in cellular redox and energy metabolism, which is why shilajit is most often used to support the mitochondria as they turn fuel into usable energy. A quality version is purified and tested for heavy metals, since sourcing is everything with a raw mineral material like this.
Why the evidence supports it
Shilajit carries a long traditional history alongside a genuinely growing research base -- placebo-controlled human trials have looked at purified shilajit for healthy testosterone levels, retained muscular strength under fatigue, bone density, and markers of new collagen formation. Mechanistically, its fulvic acid and dibenzo-alpha-pyrones are proposed to support the cell's redox balance and energy metabolism, and animal work shows it raising the body's own antioxidant enzymes. That points squarely at the cell's Transform function -- the mitochondria converting fuel into ATP. The traditional use is deep and the modern trials are encouraging, though still early and mostly small, so this reads best as a promising, well-tolerated complex rather than a settled one.
What it supports
- Supports healthy mitochondrial energy production
- Provides fulvic acid and a broad range of trace minerals
- Supports healthy mineral balance
- Supports steady everyday energy and stamina
Which function it supports
Ties to the cell's Transform function -- supporting the mitochondria, the part of the cell that converts fuel into the ATP energy your body runs on.
Learn the why behind this pillarHow it relates to your cells and mind
Every product here ties back to a specific job your body does. This one touches the functions below -- follow either link to see the mechanism in full, then dig into the studies.
What it is made of -- and the mechanisms behind it
Each ingredient acts on several of the body's functions. Taken together, this product touches these cell and mind functions -- follow any to see the mechanism in full.
The ingredients
Mechanisms drawn from our ingredient knowledge base (2 profiled ingredients). Structure and function only -- not a treatment claim.
The science on the ingredients
These studies are research on the ingredients and mechanisms in this product, not on the finished product itself, and they are shown for education. Nothing here is medical advice, and nothing here may be used to diagnose, treat, cure, or prevent any disease. Talk to your own provider about what is right for you.
- Pre-clinical evaluation of Shilajit in cancer: a systematic review
Cureus · 2026
Maps apoptosis NF-kappaB ROS and cell-cycle mechanisms -- No eligible human cancer study (Shilajit evidence)
- Effects of 12 Weeks of Chromium Phyllanthus emblica Fruit Extract and Shilajit Supplementation on Markers of Cardiometabolic Health Fitness and Weight Loss in Men and Women with Risk Factors to Metabolic Syndrome Initiating an Exercise and Diet Intervention: A Randomized Double-Blind Placebo-Controlled Trial
Nutrients · 2025
In adults doing exercise and diet changes plus chromium, amla, and shilajit, some cardiometabolic and fitness measures improved, mostly at 6 weeks. No shilajit-only arm means its individual effect is unclear.
- The Shilajit Mouthwash Effect Versus Conventional Treatment on Pain and Healing of Oral Lichen Planus: A Randomized Clinical Trial
2024
In an Iranian randomized trial of 56 oral lichen planus lesions, adding Shilajit to a triamcinolone and nystatin mouthwash gave no extra pain reduction, though lesion severity scores fell further and side effects were minimal.
- Analgesic Efficacy of Native Himalayan Shilajit as Add-On Therapy in Myofascial Pain Syndrome: An Exploratory Pilot Clinical Trial
2026
In 76 Indian adults with myofascial pain at AIIMS Rishikesh, adding 250 mg/day Himalayan shilajit for 49 days was followed by 45% lower pain scores, but the trial was open-label with no placebo arm.
- Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix Mechanisms
Journal of the American College of Nutrition · 2019
In middle-aged women, 14 weeks of oral shilajit upregulated skin genes tied to extracellular-matrix (collagen/elastin) and microvascular pathways versus baseline, indicating a structure/function effect on skin support tissue.
- Full-spectrum efficacy of cariprazine across manic and depressive symptoms of bipolar I disorder in patients experiencing mood episodes: Post hoc analysis of pooled randomized controlled trial data
Journal of affective disorders · 2024
In pooled randomized trials of adults with bipolar I disorder, cariprazine was associated with reduced manic and depressive symptom scores across both mood poles, with low rates of treatment-emergent switch to the opposite pole.
Do testosterone boosters really increase serum total testosterone? A systematic reviewEmergingSystematic review2024
Classified purified PrimaVie shilajit as only possibly effective in men with late-onset hypogonadism -- Most testosterone boosters failed; the single shilajit trial was small; industry-funded; and high risk of bias; clinical significance of hormone change was uncertain
Morgado A et al. -- International Journal of Impotence Research
Effects of 12 Weeks of Chromium Phyllanthus emblica Fruit Extract and Shilajit Supplementation on Markers of Cardiometabolic Health Fitness and Weight Loss in Men and Women with Risk Factors to Metabolic Syndrome Initiating an Exercise and Diet Intervention: A Randomized Double-Blind Placebo-Controlled TrialEmergingRandomized controlled trial2025
In adults doing exercise and diet changes plus chromium, amla, and shilajit, some cardiometabolic and fitness measures improved, mostly at 6 weeks. No shilajit-only arm means its individual effect is unclear.
Martinez V et al. -- Nutrients
Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix MechanismsClinical trial2019
In middle-aged women, 14 weeks of oral shilajit upregulated skin genes tied to extracellular-matrix (collagen/elastin) and microvascular pathways versus baseline, indicating a structure/function effect on skin support tissue.
Das A; Datta S; Rhea B; et al. -- Journal of the American College of Nutrition
Efficacy of Momiai in Tibia Fracture Repair: A Randomized Double-Blinded Placebo-Controlled Clinical TrialEmergingRandomized controlled trial2020
Mean radiographic union time 129 versus 153 days; p<0.049 -- No significant adverse-event difference; p=0.839
Sadeghi SMH et al. -- Journal of Alternative and Complementary Medicine
Shilajit-analytical study to understand the phyto complex present in shilajit raw material extract and resin by using hyphenated techniquesEstablishedTechnology-validation study2026
Hyphenated techniques differentiated material and processing forms -- No clinical efficacy or safety outcome (Shilajit evidence)
Kohli HK et al. -- Journal of Chromatography A
Rapid Determination and Quantification of Nutritional and Poisonous Metals in Vastly Consumed Ayurvedic Herbal Medicine (Rejuvenator Shilajit) by Humans Using Three Advanced Analytical TechniquesEstablishedTechnology-validation study2022
Characterized broad elemental profiles using LIBS; ICP-OES/MS; and EDX -- Several elements exceeded authors' cited permissible limits in tested samples
Aldakheel RK et al. -- Biological Trace Element Research
The physiological effects of administering different concentrations of Shilajit to Awassi lambs and their impact on productive trait and blood parameters and some biochemical measurements.EmergingAnimal study2026
Shilajit supplementation at 100 mg per kg body weight improved growth performance and stress resistance in Awassi lambs during summer heat exposure.
Agwaan HWK -- Open veterinary journal
Efficient separation of chemical constituents from shilajit by an inner-recycling counter-current chromatography and their molecular docking analysis for osteoporosis.EmergingPreclinical study2026
Chemical constituents separated from shilajit using counter-current chromatography showed molecular docking alignment with established bone-protective pharmacological targets.
Aziz S; Ali I; Hussain M; Hyder S; Khan A; Ali K; Batool S; Wang X -- Journal of pharmaceutical and biomedical analysis
Shilajit extract (ZhaXun) protects against acetaminophen-induced liver injury via modulation of the NF-κB/AKT/Caspase-3 axis.EmergingAnimal study2026
Shilajit extract alleviated acetaminophen-induced acute liver injury in rats through modulation of the NF-kB, AKT, and Caspase-3 signaling axis.
He SQ; Yang SY; Li Y; Ding R; Zhang JL; Zhong SH; Gu R -- Journal of ethnopharmacology
Investigation of the molecular and cellular effects of Shilajit on 5-fluorouracil (5-FU)-induced nephrotoxicity in rats.EmergingAnimal study2025
Shilajit showed protective effects against chemotherapy-induced nephrotoxicity in rats, improving oxidative stress parameters, protein expression, and kidney tissue structure.
Ezer M; Öztürkler M; Yıldız-Dalgınlı K; Atakişi E; Beşeren-Havadar H; Atakişi O -- Iranian journal of basic medical sciences
Efficient generation of HPLC and FTIR data for quality assessment using time series generation model: a case study on Tibetan medicine Shilajit.EmergingPreclinical study2024
A time-series data generation model improved HPLC and FTIR quality assessment methods for shilajit despite small available sample sizes.
Ding R; He S; Wu X; Zhong L; Chen G; Gu R -- Frontiers in pharmacology
Histopathological and immunohistochemical investigation of the effect of Shilajit in rats with experimental spinal cord injury.EmergingAnimal study2023
Rats with spinal cord injury given shilajit by injection into the abdomen, not orally as a supplement, showed reduced tissue-damage markers on histology compared to untreated injured rats.
Çetin E; Samcak T; Keleş ÖF; Ünlü İ; Akyol ME; Arabacı Ö -- Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
Antiviral activity of natural humic substances and shilajit materials against HIV-1: Relation to structure.EmergingPreclinical study2021
In a lab dish test against HIV-1, humic substances were far more potent (EC50 0.37 to 1.4 mg per L) than shilajit materials (EC50 14 to 142 mg per L), showing shilajit was much weaker in this assay.
Zhernov YV; Konstantinov AI; Zherebker A; Nikolaev E; Orlov A; Savinykh MI; Kornilaeva GV; Karamov EV -- Environmental research
Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment.EmergingPreclinical study2021
In lab dishes, Mumio (Shilajit) was more toxic to bladder cancer cells than to normal bladder cells, but this was a cell-culture study only, with no animal or human testing.
Kloskowski T; Szeliski K; Krzeszowiak K; Fekner Z; Kazimierski Ł; Jundziłł A; Drewa T; Pokrywczyńska M -- Scientific reports
Exploration of fulvic acid as a functional excipient in line with the regulatory requirement.EmergingAnimal study2020
Fulvic acid can form co-crystals with natural phytochemicals, supporting its potential use as a functional pharmaceutical excipient.
Gnananath K; Nataraj KS; Rao BG; Kumar KP; Mahnashi MH; Anwer MK; Umar A; Iqbal Z -- Environmental research
Hepatoprotective effects of Shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats.EmergingAnimal study2020
Shilajit improved histopathological liver changes in a rat model of high-fat-diet-induced fatty liver disease, indicating hepatoprotective mechanisms.
Ghezelbash B; Shahrokhi N; Khaksari M; Ghaderi-Pakdel F; Asadikaram G -- Hormone molecular biology and clinical investigation
Antioxidant, cytotoxic and hyperalgesia-suppressing activity of a native Shilajit obtained from Bahr Aseman mountains.EmergingAnimal study2019
Aqueous shilajit extract reduced thermal pain response in diabetic rats over six weeks compared with control groups, in a study of antioxidant and analgesic mechanisms.
Jafari M; Forootanfar H; Ameri A; Foroutanfar A; Adeli-Sardou M; Rahimi HR; Najafi A; Zangiabadi N -- Pakistan journal of pharmaceutical sciences
From Phenolic Profile to Gut Function: Comparative Effects of Region-Specific Shilajit on Selected Culturable Intestinal Microbial Groups and beta-Glucuronidase Activity-A Preliminary StudyEmergingCell-culture study2026
Reported region-dependent effects on selected culturable groups and beta-glucuronidase activity -- No human microbiome; gut barrier; symptom; immune; or clinical outcome
Kamgar E et al. -- Molecules
Mumio and bladder cancer: unlocking its potential in 3D cell cultureCell-culture study2026
In lab dishes, a Mumio formulation reduced growth and increased cell death in bladder cancer cell spheroids more than in normal bladder cells. No animal or human outcome was tested.
Fekner Z et al. -- BMC Cancer
The effects of Shilajit on periodontal ligament cells in wound healing: a comprehensive in vitro studyCell-culture study2025
In a lab dish, shilajit increased periodontal ligament cell migration, proliferation, and scratch-wound closure at 2 to 3 mg/mL. No animal or human gum-healing outcome was tested.
Alqarni A et al. -- BMC Complementary Medicine and Therapies
Accelerating effect of Shilajit on osteogenic property of adipose-derived mesenchymal stem cells (ASCs)Cell-culture study2022
Increased alkaline-phosphatase activity; osteogenic differentiation; and calcium deposition in several comparisons; alginate plus shilajit enhanced selected osteogenic-medium effects -- No animal or human bone-healing outcome; direct cell exposure cannot establish oral absorption or tissue delivery
Kangari P et al. -- Journal of Orthopaedic Surgery and Research
In search for a panacea for coronavirus disease-19: Analysis of ongoing clinical trials for the management of coronavirus disease-19 pandemic in IndiaEstablishedClinical trial2022
Among 419 COVID-19 trials registered in India, 166 tested Ayurveda and 154 what the registry calls allopathy, with hydroxychloroquine the most-trialled agent across 25 studies and nearly 18,000 participants.
Maheshwari N; Roy V -- Indian journal of pharmacology
Analgesic Efficacy of Native Himalayan Shilajit as Add-On Therapy in Myofascial Pain Syndrome: An Exploratory Pilot Clinical TrialEmergingClinical trial2026
In 76 Indian adults with myofascial pain at AIIMS Rishikesh, adding 250 mg/day Himalayan shilajit for 49 days was followed by 45% lower pain scores, but the trial was open-label with no placebo arm.
Darshan Basavaraja; Ravi Kant; Venkatesh S Pai; Rajkumar Yadav; Gaurav Chikara; Shailly Tomar; Debabrata Sircar; Katkar Rahul Sambhaji; Prasan Kumar Panda
Effects of Feed Supplementation With Fulvic Acid on the Systemic and Mucosal Protective Mechanisms of Juvenile Rainbow Trout (Oncorhynchus mykiss).EmergingRandomized controlled trial2025
A randomized controlled trial on humic and fulvic acids found that adding 0.5%-1% of fulvic acid to the feed of juvenile rainbow trout can help to improve their immune and antioxidative defenses and thereby support the wellbeing of fish.
Zavvar F; Mazandarani M; Hoseinifar SH; Jafari V; Lieke T -- Journal of animal physiology and animal nutrition
Balanced by design -- we show supporting and contradicting findings. Search all studies
No product works in isolation
Every cell function above -- Sense, Exchange, Transform, Build, Maintain, Adapt -- needs the same broad base of optimal micronutrient levels running underneath it, all the time. Panacea Shilajit is not a stand-alone fix; it is one piece that plugs into that larger system. The foundation comes first, and this supports it.
Stacks well with
Pick your goal -- here is what Panacea Shilajit pairs with for each. Nothing works in isolation; these share the same systems.
For Energy & Mitochondria
For Minerals
For Detox
For Women's Health
Ready-made stacks it is part of
Foundational, or targeted?
Not everything in the shop is meant to be taken forever. Some products here are foundational -- a daily nutrient base built for long-term, ongoing use. Others are targeted -- shorter-term support for a specific season, not a lifelong habit. If you are not sure which one this is, that is a fair question to ask us before you buy.
Learn more, on your terms
Do not take our word for it -- go read. Each topic below opens a pre-loaded search so you can explore the nutrient, the mechanism, or the device for yourself.
Search the full studies libraryHow to use it
Dissolve the small labeled serving in warm water and drink, usually once a day, earlier rather than late since some people find it energizing. Follow the brand's serving size.
Use code HOLISTICLOVE at checkout.
Where to get it
We are lining up the best way to get this one to you. In the meantime, reach out and we will point you the right way -- or browse the full shop to see every product.
See the full shopThe studies
See the research behind the science we point to.
Explore studiesThe blog
Plain-language reads on how it all fits together.
Read the blogOptimal nutrients are the definition of longevity
Long-term cell function depends on having what it needs, at the level it needs it, for as long as it needs it. That is the whole thesis behind everything we point you to here.
When you buy through our links, we earn a small commission -- and that is what funds all the free education here. It never costs you more. Products are not intended to diagnose, treat, cure, or prevent any disease.
Panacea Shilajit is a purified fulvic and humic mineral complex traditionally sourced from mountain rock, naturally rich in fulvic acid and trace minerals. It is often used to support the mitochondria as they turn fuel into usable energy. It fits people who want a whole-complex, traditional material with a long history of use.
FAQ
What does Panacea Shilajit support?
It supports healthy mitochondrial energy production, provides fulvic acid and a broad range of trace minerals, supports healthy mineral balance, and supports steady everyday energy and stamina.
How do I take it?
Dissolve the small labeled serving in warm water and drink, usually once a day and earlier rather than late, since some people find it energizing. Follow the brand's serving size.
What makes it different?
Sourcing and testing are everything with a mineral material like this, so a good brand tests it for purity and heavy metals. That transparency is what earns it a place.